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La Nopalera Mexican Restaurant San Marco
About Us
La Nopalera Mexican Restaurant – San Marco, located in the heart of Jacksonville, FL, has been proudly serving Duval and St. John's counties since 1996. Known for our vibrant atmosphere and authentic Mexican cuisine, we offer a flavorful menu featuring tacos, burritos, sizzling fajitas, fresh guacamole, and handcrafted margaritas. Join us for happy hour specials, live music, and outdoor patio seating perfect for any occasion. Whether you're dining with friends, enjoying a family meal, or celebrating something special, La Nopalera is your go-to destination for bold flavors and great vibes. Call us at 904-399-1768 to place an order or make a reservation today!
Areas Served
Jacksonville, FL | Downtown | Riverside, Jacksonville, FL | San Marco, Jacksonville, FL | Baymeadows, Jacksonville, FL | Arlington, Jacksonville, FL | San Jose, Jacksonville, FL | Duval County, FL | St. Johns County, FL
Languages Spoken
- English
- Spanish
What We Offer
Our Specialties include:
- Authentic Mexican Food
Our Services include:
- Lunch and Dinner
- Vegetarian Options Available
- Happy Hour
- Drink Specials
- Live Music
- Patio Seating
- Sports Viewing
- Takeout
- Online Ordering
- Catering
Our Brands include:
- White Claw
- Blue Moon
- Corona
- Dos Equis
- Tecate
- Modelo
Our Products include:
- Tacos
- Burritos
- Fajitas
- Guacamole
- Queso
- Imported and Domestic Beers
- Margaritas
- Tequila
- Liquor
- Frozen Drinks
Testimonials
On 1/8/2026
Ashley Madore
had this to say:
Food: 10/10 fresh food and big portion
Service: 10/10 the staff’s are very helpful and nice
Atmosphere: nice and big place
On 1/2/2026
Jeff Card
had this to say:
Foods always on point
On 12/31/2025
Oralia González
had this to say:
(Translated by Google) Everything was delicious!!
(Original)
Delicioso todo!!
On 12/25/2025
Lorenda
had this to say:
Awesome location, great food
On 12/22/2025
Valerie Frederick
had this to say:
I dont what is called but it was fantastic. I would definitely get it again.
Contact Us
La Nopalera Mexican Restaurant San Marco
1434 Hendricks Ave Jacksonville, FL 32207
Phone: (904) 399-1768
Email: lanop2sanmarco
Next to the rail road in San Marco,
Behind Panera Bread
Where To Find Us
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Payment Types Accepted
Visa, MasterCard, American Express, Discover, Debit Cards, Apple Pay, Android Pay
Our Hours
Holiday Hours May Vary. Please Call For Details.
Monday: 11:00 AM - 10:00 PM
Tuesday: 11:00 AM - 10:00 PM
Wednesday: 11:00 AM - 10:00 PM
Thursday: 11:00 AM - 10:00 PM
Friday: 11:00 AM - 11:00 PM
Saturday: 11:30 AM - 11:00 PM
Sunday: 11:30 AM - 9:30 PM
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